RESTYLANE without Lidocaine - hyaluronic acid used for mid-size wrinkles filling. RESTYLANE without Lidocaine is made of stabilised hyaluronic acid of non-animal origin. RESTYLANE with Lidocaine has mid-size molecules. The filler is injected in mid-layer of dermis, and it reduces deep wrinkles. RESTYLANE with Lidocaine is used for filling mid-size wrinkles, including nasolabial fold, forehead, acne scars, lips and laughter wrinkles.